EFFICIENT POSTERIOR PROBABILITY MAPPING USING SAVAGE-DICKEY RATIOS.



An epigenetic switch ensures transposon repression upon dynamic loss of DNA methylation in embryonic stem cells

DNA methylation is extensively remodeled during mammalian gametogenesis and embryogenesis.Most transposons become hypomethylated, raising the question of their merlin wizard costume regulation in the absence of DNA methylation.To reproduce a rapid and extensive demethylation, we subjected mouse ES cells to chemically defined hypomethylating culture

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